The relevant question is whether the subject of the offense is noteworthy and action-worthy. "Just don't interact with what offends you" is worthless advice to targets of anti-Semitism and other forms of racism, misogyny, homophobia and transphobia in general, for example, because of the difficulty of finding places where you won't encounter those things or apologists for those things.
In those cases it's often necessary for people to stand up and demand larger change and measures against hate speech. In Twitter's case, since advertisers tended to listen to the majority of people who don't want those things cluttering a site, commerce was sometimes an effective lever. People used it, and rightly so. Those who got off on that kind of hate speech were often frustrated because they really didn't have similar economic leverage -- "get woke, go broke" was an aspirational statement that usually led to targeted properties making more money rather than less -- but so be it.
There were, of course, also cases where people affected to be "offended" by any number of things a target was supposed to have done that were actually just exaggerated or outright made up. That's where the collective power of Twitter could be derailed into toxic open-ended bullying campaigns that ("oddly") mostly targeted women or transwomen (Lindsay Ellis and Natalie Wynn being notable examples) and were, at their root, about basically nothing. That was one of the very shittiest things about Twitter, which never really made an effort to give users even the very simple means of breaking up troll-storms that are available to a user on, say, FaceBook or Instagram.
(Also annoying, and related: Twitter's "enemy of the day" phenomenon where a bunch of people would pile on someone who had supposedly sinned. Sometimes the subject had actually done something, sometimes they hadn't, sometimes "something" had happened that was amplified wildly out of proportion, but the overall vibe was always the same: multitudes of people showing up to self-promote while pretending to be righteous. Ugh.)